The adult garden wolf spider can inject a mild venom into its prey or potential threats through its fangs. This venom can induce discomfort and mild reactions in humans, and similarly, can affect dogs, cats, and smaller mammals. Birds and insects may experience more significant impact due to their smaller body sizes. The primary way garden wolf spider uses its toxin is through biting, and its effects can vary widely between different groups of animals, although it typically does not cause severe harm to larger animals.

Garden wolf spider typically does not exhibit routine biting behavior towards humans. When bites occur, they are usually a defensive response by the adult spider feeling threatened. The bite, employing their fangs, may result in mild, localized immediate consequences.

Garden wolf spider, being part of the Araneae order and Lycosidae family, does not usually bite humans. Encounters leading to bites are typically due to defensive reactions when they feel threatened. This species may live in areas frequented by humans, raising the odds of unintentional interactions that could provoke garden wolf spider to bite as a means of self-protection.

To prevent adverse encounters with garden wolf spider, it's essential to avoid their habitats and be mindful of their presence. Keeping living spaces clear of clutter can deter garden wolf spider from settling in. Regular cleaning and proper storage of items where garden wolf spider might seek refuge can effectively minimize the likelihood of coming into close contact with them.

In the event of a defensive bite from garden wolf spider, cleaning the area with soap and water and applying a cold compress can ease immediate distress. Ensuring that the affected area is kept clean and avoiding disturbing it allows for natural recovery. Use of personal protective equipment while handling items where garden wolf spider may reside can further prevent incidents during recovery.