Thistledown Velvet Ant do not typically sting humans out of aggression; stings often occur when threatened or accidentally disturbed. Only females have stingers, which they can use effectively against humans. A sting can be painful and cause redness, swelling, and itching. Repeated stings have no physical consequences for thistledown Velvet Ant unlike bees, which die after stinging.

Thistledown Velvet Ant do not sting humans out of aggression. However, humans may inadvertently threaten or disturb thistledown Velvet Ant, especially if they are not aware of thistledown Velvet Ant's presence. Female thistledown Velvet Ant possess the ability to sting, which can lead to uncomfortable reactions such as pain, redness, swelling, and itching upon unintentional contact.

To prevent accidental encounters with thistledown Velvet Ant, it is crucial to maintain a clean environment. Reducing clutter and sealing cracks can deter thistledown Velvet Ant from entering human habitats. Wearing protective clothing when in areas where thistledown Velvet Ant is likely to be present and staying vigilant can also reduce the risk of unintentional disturbances.

In case of being stung by thistledown Velvet Ant, promptly washing the affected area with soap and water can help reduce potential irritation. Applying a cold compress may alleviate swelling and discomfort. It's advisable to keep the affected area clean, avoid scratching to prevent secondary infections, and stay calm as distress might exacerbate the symptoms. Additionally, people who are stung should monitor the reaction and seek professional help if symptoms persist or worsen. During recovery, avoid exposing the affected area to further disturbances.