Northern jewelled spider possesses a mild venom that it delivers through bites using its fangs. The toxin primarily functions to subdue its prey and deter predators. When humans or domestic animals like dogs and small mammals encounter northern jewelled spider, they may experience minor symptoms such as localized pain or swelling. The venom is more effective against smaller animals, which may suffer more serious consequences. Adult northern jewelled spider are capable of envenomating and the likelihood of a reaction varies across different animal groups.

Northern jewelled spider is not known to exhibit biting behavior towards humans. Typically, bites occur in self-defense and are exceptionally rare. If such an event occurs, the consequences tend to be mild due to northern jewelled spider's non-aggressive nature towards humans.

Northern jewelled spider typically do not pose a significant threat to humans as they rarely exhibit biting behavior. However, in the uncommon event that a bite occurs, usually in self-defense, it could cause mild discomfort. Understanding that northern jewelled spider only bite when they feel threatened can help in mitigating potential negative interactions.

To prevent the rare but possible troubles caused by northern jewelled spider, minimize contact with their habitats. Ensure that homes and spaces are kept free of inviting nooks by practicing regular cleaning. Utilize physical barriers like screens on windows and doors to deter northern jewelled spider from entering living areas.

In the unusual circumstance of experiencing discomfort due to northern jewelled spider, keeping the affected area clean and avoiding the urge to scratch can prevent additional irritation. Employing a cold compress may help alleviate discomfort. It is important to monitor the area and allow it time to heal, while also making sure to maintain a clean environment to discourage further encounters with northern jewelled spider.