Typically, walnut orb-weaver spider intoxicates by injecting venom through its fangs when biting. The venom is only mildly toxic, serving as a defense mechanism to deter potential threats rather than for hunting. Humans, dogs, cats, and other small mammals might experience minor irritation or slight discomfort if bitten. Similarly, birds, lizards, and amphibians could suffer local effects. For insects, the venom may be more disabling, interrupting their muscle control or causing more significant harm due to their smaller size and different physiology.

Walnut orb-weaver spider typically does not exhibit aggressive behavior towards humans. Bites are extremely rare, generally occurring only in self-defense if the spider feels threatened. Due to their timid nature, adults may bite as a last resort, using their fangs. The consequence of a bite is usually mild, resulting in minimal discomfort.

Walnut orb-weaver spider, by nature, is not aggressive towards humans and bites are very rare, mostly occurring if they feel threatened or are provoked. Given their shy demeanor, they may resort to biting when they have no other option to escape. Such incidents happen infrequently because these creatures typically avoid human contact.

Preventing unpleasant encounters with walnut orb-weaver spider involves minimizing their habitats around living spaces. This includes clearing clutter where they might hide, regularly cleaning dark corners and crevices, and using window screens to prevent them from entering homes. Proper outdoor lighting can also deter walnut orb-weaver spider from getting too close.

If an undesired encounter with walnut orb-weaver spider does occur, easing any discomfort can usually be managed with simple and safe measures. Cleaning the area gently with soap and water, then applying a cold compress can help soothe the area. Maintaining cleanliness of the affected site is crucial for recovery. It's wise to monitor for symptoms and maintain a clean and calm environment to minimize distress.