Big-headed ant is not characteristic for biting humans. If disturbed, it could defensively bite, but this is atypical. Bites, although rare, could cause mild irritation due to their method of biting and injecting formic acid as a defense mechanism. Typically, big-headed ant would rather retreat than engage with humans, so bites are incidental, not habitual.

Big-headed ant often seek shelter in human dwellings, driven by their search for food and suitable nesting sites. Their preference for warm climates means they frequently inhabit homes in these regions. When inside, big-headed ant contaminate foodstuffs, potentially chew through materials like electrical wiring—which can cause fire hazards—and even cause structural damage. Their large colonies multiply quickly, escalating problems from mere annoyances to significant infestations.

Preventing issues with big-headed ant involves creating barriers to entry. Seal cracks and crevices in walls and foundations. Ensure window screens are intact. Regular cleaning helps remove food residues that attract big-headed ant. Store food in airtight containers to deter infestations. Manage waste efficiently and limit standing water within the home to make environments less hospitable for big-headed ant colonies.

Once big-headed ant are present, maintain sanitation by cleaning up spills and crumbs promptly to remove food sources. For electrical wiring protection, inspect wiring regularly and use pest-resistant materials where possible. Physical removal or vacuuming can reduce big-headed ant numbers. Employing pest control professionals can be safer and more effective for significant problems. Post-encounter, maintain a clean environment to discourage return and pay attention to any signs of recurring big-headed ant activity.

At both adult and larval stages, big-headed ant compromises the integrity of houses and can chew through electrical wiring, posing fire hazards. Infestations often lead to food contamination. Their presence ranges from mild annoyance to severe structural damage, depending on infestation size.

Big-headed ant, commonly found in warmer regions, often invades homes searching for food. They cause distress to humans by contaminating food and being aggressive. Their omnipresence in human habitats can result in a range of annoyances from mild inconvenience to severe pest management challenges.