The adult red velvet jumping spider secretes venom through its fangs, which may cause mild discomfort in some animals when bitten. While this venom primarily acts as a defense and prey incapacitation mechanism, its mild nature usually results in minor symptoms in humans and dogs. In smaller animals, such as insects, the venom can be more hazardous, potentially leading to their immobilization or demise. The effect of the venom varies among different animal groups, reflecting the specialized role it plays in the organism's survival strategy.

Red velvet jumping spider does not characteristically bite humans. Bites toward humans are exceptional, primarily in self-defense or when feeling threatened. Typically, red velvet jumping spider avoids humans and employs biting chiefly to subdue prey. Human encounters that result in bites are rare, with consequences usually being mild and not medically significant.

Red velvet jumping spider, by nature, rarely interacts with humans, preferring to reserve its bites for capturing prey. However, the discomfort to humans occurs when it feels threatened or is acting in self-defense, typically if involuntary contact is made. These encounters, albeit infrequent, could be alarming, causing mild and typically non-threatening symptoms.

To avert undesired encounters with red velvet jumping spider, it's effective to deter them from inhabiting human dwellings by maintaining a clean environment. Reducing clutter and sealing cracks in walls reduces shelter opportunities for red velvet jumping spider, thus decreasing the chance of coming into close contact with them at home.

In the uncommon event of an encounter with red velvet jumping spider, remaining calm is paramount; these creatures are not aggressive towards humans. To minimize discomfort, gently brushing the red velvet jumping spider away instead of swatting can help avoid provoking it. Post-encounter, keeping the affected area clean and applying a cool compress can relieve discomfort. It's also recommended to monitor the site for changes and maintain a clean environment to prevent further occurrences while being mindful not to disturb their natural habitat where possible.