The species leaf curling spider can affect a variety of animals, including mammals like humans, dogs, and cats, as well as birds and insects, by delivering venom through its fangs. This venom is generally mild and primarily used for subduing prey rather than for aggressive defense. While larger animals such as humans might only experience minor discomfort or localized reactions upon being bitten, smaller creatures, particularly insects, may suffer more severe consequences, potentially being paralyzed or killed by the toxin, especially considering that adults of leaf curling spider are the toxic stage.

Leaf curling spider typically does not exhibit biting behavior towards humans. Instances of leaf curling spider biting humans are rare and usually occur as a defensive response when they feel directly threatened. The immediate effect of a bite is typically mild, with no severe consequences for human health.

Leaf curling spider generally avoids human interaction, but may bite if they feel threatened. Human encounters can occur when disrupting their web or habitat. While rare and not usually health-threatening, their bites can cause discomfort or mild reactions in some individuals, leading to the need for simple prevention and solutions.

To prevent unwelcome encounters with leaf curling spider, maintain cleanliness to deter insects which leaf curling spider prey on. Regularly remove webs from around your home and garden. Utilize window screens and seal cracks to prevent leaf curling spider from entering. Avoid handling leaf curling spider directly and be cautious when moving stored items or working in dense vegetation.

After an encounter with leaf curling spider, keeping the affected area clean is crucial. Wash gently with soap and water to minimize the risk of infection. Apply a cold compress to reduce mild swelling or discomfort. During recovery, avoid scratching the area to prevent skin damage or further irritation. Monitor for signs of infection, such as excessive redness or swelling, and consult a professional if concerns arise.