Dotted wolf spider typically delivers its toxin through bites using its fangs. The venom, with milder intensity, can affect humans, causing discomfort or mild reactions. Mammalian pets and smaller mammals may experience similar mild symptoms upon envenomation. Additionally, various insects might be more significantly impacted due to their smaller size and different physiology. The toxicity, however, generally poses low risks and severe complications are rare in the affected animals.

Dotted wolf spider typically does not bite humans. Bites are rare and primarily defensive, occurring only when provoked or threatened. If a bite does happen, the method involves a quick bite with their fangs, and the immediate consequence is usually mild irritation or localized pain, given dotted wolf spider's non-aggressive nature towards humans.

The species dotted wolf spider may cause trouble to humans due to their defensive behavior when they feel threatened. Although dotted wolf spider usually avoids interaction with humans, if they are provoked or feel cornered, they might bite as a means of self-defense. This can occur during accidental encounters like when a human inadvertently comes into contact with them.

To prevent the troubles caused by dotted wolf spider, it is recommended to avoid their habitats and to be vigilant when moving objects where they might reside. Using protective clothing and gloves during such activities can minimize risks. Sealing entry points to homes and maintaining clean, clutter-free spaces discourage dotted wolf spider from settling in living areas.

If trouble arises due to dotted wolf spider, immediately washing the affected area with soap and water can reduce the risk of infection. Applying an ice pack helps to ease any discomfort. Keeping the affected area elevated may also alleviate symptoms. It is important to avoid scratching the site to prevent secondary infection. During recovery, maintain cleanliness and monitor the area for changes. If symptoms escalate, seek professional advice.