Tapinoma subtile typically utilizes its toxicity primarily as a means to immobilize and predigest prey, rather than for defense. Through its mouthparts, tapinoma subtile delivers a mild venom that can affect other small animals, particularly various insects and some arthropods. When these animals are bitten, they may experience paralysis or other physiological disruptions, depending on the potency of the venom and the specific biological reactions of the animal involved. The toxic effects are prevalent during the adult stage of tapinoma subtile's life cycle.

Tapinoma subtile tend to enter homes attracted by food sources, especially sweets and proteins. Their small size allows them to infiltrate through tiny cracks and crevices. Once inside, they establish nests and recruit more tapinoma subtile to the site, leading to a persistent infestation which can be distressing and unhygienic for residents.

To deter tapinoma subtile from invading homes, ensure food is stored in sealed containers and clean up food residues promptly. Seal any potential entry points like cracks and crevices. Using natural deterrents like vinegar or peppermint oil around entry points can also help as tapinoma subtile tend to avoid these smells.

Once tapinoma subtile have entered the home, maintain cleanliness by wiping surfaces to remove food traces and pheromone trails. Use baiting traps designed for tapinoma subtile as a non-toxic method to control the population. Regularly inspect and remove potential indoor nesting sites. During recovery from an infestation, be vigilant and maintain these practices to prevent re-infestation.

Tapinoma subtile can be a significant nuisance in their adult stage, often infiltrating homes in search of sweets or protein-rich foods. Their tendency to nest indoors and their persistent foraging behaviors can lead to a persistent presence, causing distress to residents.