Blackjacket's sting contains venom that can cause pain and inflammation in humans. The venom's toxins, aimed at defense and predation, can lead to neurotoxic effects. Mild encounters usually result in temporary discomfort, while severe stings might trigger more intense and lasting symptoms, but typically not life-threatening unless in cases of extreme envenomation or secondary complications.

Blackjacket typically inflicts pain and discomfort on other animals it encounters, via a sting that can inject toxins. The intensity of the toxicity ranges from mild to severe, primarily affecting both humans and a variety of other animals, with adults being the toxic stage. When humans or mammals like dogs come into contact with blackjacket, they may experience significant pain, swelling, or even severe reactions requiring medical attention. Smaller animals such as rodents or insects could suffer fatal outcomes when exposed to the toxin.

Blackjacket only stings when threatened or their nest is disturbed, primarily to defend their colony. Females possess the stinging capability; males don't. The sting injects venom, causing pain and potential allergic reactions in humans. Stinging has no adverse effects on blackjacket as their stingers are not barbed unlike those of honeybees.

The species identified can bring trouble to humans primarily when they feel their territory is threatened, typically around their nesting sites. They may also interact with humans during outdoor activities, such as picnics or barbecues, as they are attracted to food sources. Intentional or accidental disturbances to their nests can result in the defensive stinging behavior, leading to discomfort and, in rarer cases, more serious reactions.

To prevent issues with the identified species, ensure food is covered during outdoor activities to reduce attraction. Regularly inspect and manage potential nesting sites around homes and gardens. Keeping a tidy environment with minimal exposed waste can discourage nesting near human habitats. Use of protective clothing and non-intrusive measures to ward off these insects can be helpful when spending time outdoors.

When faced with discomfort caused by the pest, it is essential to keep the affected area clean and to apply a cold compress to soothe the site. One can also use a paste of baking soda and water to alleviate discomfort. To minimize adverse consequences, it is critical to avoid disturbing the area further and allow time for recovery. During this period, keep the affected limb elevated if possible and practice good hygiene to prevent secondary infections.

Blackjacket can become a significant nuisance, especially as adults. Often encountered at outdoor activities, these pests may aggressively defend their nests or scavenge for human foods, leading to mild to severe distress among people.