The species whitebanded orbweb spider is noted for its mild toxicity, predominantly affecting animals through bites with its fangs. Adult whitebanded orbweb spider typically deploy venom to subdue prey or in self-defense. While humans may experience mild discomfort, animals like dogs or birds might display more pronounced reactions to the toxin. Other spiders can also be susceptible, underlining the varied impact across different animals, with consequences ranging from negligible to moderate, depending on the victim's size and resilience to the toxin.