Mouse spider harbors a mild venom that is delivered through its fangs when biting. In adults, this venom serves a dual function, aiding in both subduing prey and defense. Typically, smaller mammals may experience mild discomfort and localized swelling upon being bitten. However, insects, which often fall prey to mouse spider, may be paralyzed or killed. Humans and larger animals like dogs and cats usually suffer minimal effects, usually no more than a temporary pain or irritation at the site of the bite.

Mouse spider is not known to exhibit biting behavior towards humans. Instances of mouse spider biting humans are extremely rare and generally only occur when these animals are provoked or handled, as a defensive reaction. As an adult, their bites are mild and without significant consequences.

Mouse spider generally do not pose a threat to humans. Troubles arise when humans accidentally provoke mouse spider, leading to defensive behavior. Mouse spider's habitat may sometimes overlap with human dwellings, increasing the likelihood of such encounters. However, bites are rare and typically result from unintentional contact with mouse spider rather than aggressive behavior on their part.

To prevent encounters with mouse spider, maintain a clean and clutter-free environment to dissuade them from entering living spaces. Regular vacuuming and dusting can disrupt potential hiding spots. Installing screens and sealing cracks can also deter mouse spider from coming indoors, reducing the likelihood of accidental provocation and consequent troubles.

If troubles with mouse spider occur, calmly and safely removing them from the immediate vicinity can be an effective solution. Utilize non-toxic methods for capturing and releasing mouse spider outdoors. Ensuring that living spaces are well-lit and reducing hiding places can discourage mouse spider from returning. During recovery, staying clear of known habitats of mouse spider minimizes further encounters. Always handle these creatures with care and respect.